Oh that is a difficult question to answer. It is dependent on two things; the person and the drug.
Certain drugs are more addictive then others, such as heroine of methamphetamine. They can become addictive even if you use them once.
Slightly less addictive drugs, marijuana is usually only addictive it you take it quite a lot. However it has been known for people to become addicted even after trying it once.
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